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ANZCOTR C/- St Vincents Hospital Sydney, Heart Transplant Unit
Darlinghurst 2010
NSW AU
Tel 61 2 8382 3071
Fax 61 2 9332 4267

About Us

About us

The Australian and New Zealand Cardiothoracic Organ Transplant Registry was established at the first annual meeting of the Australian and New Zealand Cardiothoracic transplant group in Brisbane in May 1991. The relevance of the existing International Heart and Lung Transplant Registry to Australasia is limited by differences in health care systems and varying standards of contributing centres. Consequently, the ANZCOTR aimed to report the local experience, including data on donors as well as recipients, for interested medical personnel and government. The advent of the website now enables this information to be easily accessible to everyone, including members of the public and patients.
An annual report (available in pdf and powerpoint formats) is produced by June of each year and is able to be downloaded from this site.

Data on new transplants along with updates relating to previous recipients is continuously supplied by Transplant Coordinators at the Alfred Hospital (Melbourne), Auckland City Hospital (New Zealand), Prince Charles Hospital (Brisbane), Royal Perth Hospital, Royal Children’s Hospital (Melbourne) and St Vincents Hospital (Sydney).
The Registries main office is currently situated in the Heart and Lung transplant unit, L4 Xavier building, St Vincents Hospital, Darlinghurst, Sydney, Australia.

The Registry was funded by St Vincent’s Hospital Sydney up to 1997.
After this date, Registry activity was dormant due to lack of resources.

Since 2003, the Registry secured funding from the Australian Commonwealth Government Department of Health and Ageing.

Current Registry Director is Senior Transplant Cardiologist and Heart Failure Principle Researcher Professor Anne Keogh.

Committee members are drawn from each of the six contributing Centres and meet normally by teleconference at least once per year.

Methods

A standardized data collection sheet for each individual patient is completed by the Transplant doctors or Transplant Coordinators of each transplant centre and submitted to the Registry (currently located at St Vincents Hospital) for central analysis. Information on each recipient include demographic data, survival, waiting times, factors which may affect survival such as blood group, gender, pretransplant symptom status, age, peak panel reactivity pre-operatively and cross-match status with donor.
Information on initial immunosuppressive protocol, histocompatibility with donor, and cause of death were also recorded. Donor data included demographic details, ischemic time, blood group and HLA typing.
At present, all data are entered into a specifically designed cardiothoracic transplant database (P.Oyer and E.Dong, Stanford University Hospital, California) running on a Fox Pro 2 database. Actuarial survival curves are constructed by the Cutler-Edere method and differences compared by Cox-Mantel testing. A p value of ≤0.05 is considered significant. Absolute data are presented as mean (±standard deviation) and median values.

The Registry is currently designing a new modern database to house Registry information, to be built using Filemaker Pro v8.5 and rolled out to all interested transplant centres. The estimated time required to complete the database and rollout is late 2008.